Details for gene set BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB
Phenotype	phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS
Enrichment Score (ES)	-0.79580176
Normalized Enrichment Score (NES)	-1.473936
Nominal p-value	0.053452116
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP2K1	19082	3065	0.055	-0.1441	No
2	HRAS	4868	3102	0.053	-0.1260	No
3	EGFR	1329 20944	4992	0.015	-0.2218	No
4	SPRY1	15606 1901	5245	0.013	-0.2303	No
5	CBL	19154	5255	0.013	-0.2258	No
6	SHC1	9813 9812 5430	5728	0.011	-0.2471	No
7	SOS1	5476	5800	0.010	-0.2470	No
8	SPRY2	21725	8458	0.003	-0.3889	No
9	PTPRB	19875	8579	0.002	-0.3945	No
10	SRC	5507	8725	0.002	-0.4016	No
11	RASA1	10174	8933	0.002	-0.4121	No
12	RAF1	17035	12094	-0.005	-0.5802	No
13	SPRY4	23448	14922	-0.018	-0.7253	No
14	EGF	15169	15648	-0.032	-0.7521	Yes
15	MAPK3	6458 11170	15861	-0.039	-0.7487	Yes
16	GRB2	20149	16030	-0.047	-0.7400	Yes
17	MAPK1	1642 11167	17069	-0.135	-0.7451	Yes
18	MAP2K2	19933	17495	-0.205	-0.6909	Yes
19	SH3KBP1	2631 12206 7189	18578	-1.998	0.0020	Yes

Fig 3: BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS: Random ES distribution
Gene set null distribution of ES for BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS